Endocrine Abstracts

Objectivs: Plasma NT-proBNP is inversely associated with BMI in patients with heart failure (HF). A possible mechanism may be the lipolytic effect of natriuretic peptides on abdominal fat.Myostatin is previously described as a negative regulator of skeletal muscle mass in cachexia.We assessed the hypothesis that body composition is related to plasma NT-proBNP and that myostatin levels are associated with loss of fat free mass (FFM)...

Introduction: α-Defensins are recently described peptides, which are part of the innate immune system. Increased circulating levels are observed in conditions associated with chronic low grade inflammation, such as ischemic heart disease and in diabetes mellitus (DM). Recently we reported adverse prognostic implications of high α-defensins in patients with type 1 DM. However, it is not clear whether this finding may be generalized to include other groups such as pati...

Introduction: Heart failure is characterised by an up-regulation of neurohoromones, and brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) are well-established diagnostic biomarkers with substancial prognostic value. Adrenomedullin is a vasoactive peptide and a potential biomarker of vascular injury in patients with cardiovascular disease (CVD) The aims of the present study were to investigate whether mid-regional pro adrenomedullin (MR-proADM) is predictive ...